A Virus with a Bisegmented Double-stranded RNA Genome in Rat (Oryzomys nigripes) Intestines
نویسندگان
چکیده
منابع مشابه
Disruption of Specific RNA-RNA Interactions in a Double-Stranded RNA Virus Inhibits Genome Packaging and Virus Infectivity
Bluetongue virus (BTV) causes hemorrhagic disease in economically important livestock. The BTV genome is organized into ten discrete double-stranded RNA molecules (S1-S10) which have been suggested to follow a sequential packaging pathway from smallest to largest segment during virus capsid assembly. To substantiate and extend these studies, we have investigated the RNA sorting and packaging me...
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Single-stranded RNA (ssRNA) is the simplest form of genetic molecule and constitutes the genome in some viruses and presumably in primitive life-forms. However, an innate and unsolved problem regarding the ssRNA genome is formation of inactive double-stranded RNA (dsRNA) during replication. Here, we addressed this problem by focusing on the secondary structure. We systematically designed RNAs w...
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ژورنال
عنوان ژورنال: Journal of General Virology
سال: 1988
ISSN: 0022-1317,1465-2099
DOI: 10.1099/0022-1317-69-11-2749